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Bromine is an essential trace element for assembly of collagen IV scaffolds in tissue development and architecture

Bromine is ubiquitously present in animals as ionic bromide (Br(−)) yet has no known essential function. Herein, we demonstrate that Br(−) is a required cofactor for peroxidasin-catalyzed formation of sulfilimine crosslinks, a post-translational modification essential for tissue development and arch...

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Detalhes bibliográficos
Main Authors: McCall, A. Scott, Cummings, Christopher F., Bhave, Gautam, Vanacore, Roberto, Page-McCaw, Andrea, Hudson, Billy G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144415/
https://ncbi.nlm.nih.gov/pubmed/24906154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.05.009
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