Crystal and molecular structure of paclitaxel (taxol).
Paclitaxel (formerly called taxol), an important anticancer drug, inhibits cell replication by binding to and stabilizing microtubule polymers. As drug-receptor interactions are governed by the three-dimensional stereochemistries of both participants, we have determined the crystal structure of pacl...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1995
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41442/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7624344/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.15.6920 |
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