STAT3 activation by cytokines utilizing gp130 and related transducers involves a secondary modification requiring an H7-sensitive kinase.

Ciliary neurotrophic factor, oncostatin M, leukemia-inhibitory factor, and interleukin 6 are related cytokines that initiate signaling by homodimerizing the signal-transducing receptor component gp130 or by heterodimerizing gp130 with a gp130-related receptor component. Receptor dimerization in turn...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Boulton, T G, Zhong, Z, Wen, Z, Darnell, J E, Stahl, N, Yancopoulos, G D
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1995
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41441/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7624343/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.15.6915
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