Effects of early versus delayed initiation of antiretroviral treatment on clinical outcomes of HIV-1 infection: results from the phase 3 HPTN 052 randomised controlled trial

BACKGROUND: Use of antiretroviral treatment for HIV-1 infection has decreased AIDS-related morbidity and mortality and prevents sexual transmission of HIV-1. However, the best time to initiate antiretroviral treatment to reduce progression of HIV-1 infection or non-AIDS clinical events is unknown. W...

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Main Authors: Grinsztejn, Beatriz, Hosseinipour, Mina C, Ribaudo, Heather J, Swindells, Susan, Eron, Joseph, Chen, Ying Q, Wang, Lei, Ou, San-San, Anderson, Maija, McCauley, Marybeth, Gamble, Theresa, Kumarasamy, Nagalingeshwaran, Hakim, James G, Kumwenda, Johnstone, Pilotto, Jose H S, Godbole, Sheela V, Chariyalertsak, Suwat, de Melo, Marineide Gonçalves, Mayer, Kenneth H, Eshleman, Susan H, Piwowar-Manning, Estelle, Makhema, Joseph, Mills, Lisa A, Panchia, Ravindre, Sanne, Ian, Gallant, Joel, Hoffman, Irving, Taha, Taha E, Nielsen-Saines, Karin, Celentano, David, Essex, Max, Havlir, Diane, Cohen, Myron S
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144040/
https://ncbi.nlm.nih.gov/pubmed/24602844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1473-3099(13)70692-3
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