Toll-like receptor 4 and MAIR-II/CLM-4/LMIR2 immunoreceptor regulate VLA-4-mediated inflammatory monocyte migration

Inflammatory monocytes play an important role in host defense against infections. However, the regulatory mechanisms of transmigration into infected tissue are not yet completely understood. Here we show that mice deficient in MAIR-II (also called CLM-4 or LMIR2) are more susceptible to caecal ligat...

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Autores principales: Totsuka, Naoya, Kim, Yun-Gi, Kanemaru, Kazumasa, Niizuma, Kouta, Umemoto, Eiji, Nagai, Kei, Tahara-Hanaoka, Satoko, Nakahasi-Oda, Chigusa, Honda, Shin-ichiro, Miyasaka, Masayuki, Shibuya, Kazuko, Shibuya, Akira
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Pub. Group 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143930/
https://ncbi.nlm.nih.gov/pubmed/25134989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5710
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