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Sources of superoxide/H(2)O(2) during mitochondrial proline oxidation

p53 Inducible gene 6 (PIG6) encodes mitochondrial proline dehydrogenase (PRODH) and is up-regulated several fold upon p53 activation. Proline dehydrogenase is proposed to generate radicals that contribute to cancer cell apoptosis. However, there are at least 10 mitochondrial sites that can produce s...

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Detaylı Bibliyografya
Asıl Yazarlar: Goncalves, Renata L.S., Rothschild, Daniel E., Quinlan, Casey L., Scott, Gary K., Benz, Christopher C., Brand, Martin D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143814/
https://ncbi.nlm.nih.gov/pubmed/25184115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2014.07.003
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