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Analysis of Genetic Analysis Workshop 18 data with gene-based penalized regression

Under the premise that multiple causal variants exist within a disease gene and that we are underpowered to detect these variants individually, a variety of methods have been developed that attempt to cluster rare variants within a gene so that the variants may gather strength from one another. Thes...

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Autori principali: Ayers, Kristin L, Cordell, Heather J
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143805/
https://ncbi.nlm.nih.gov/pubmed/25519325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-8-S1-S43
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