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Deep sequencing reveals the eight facets of the influenza A/HongKong/1/1968 (H3N2) virus cap-snatching process

The influenza A virus RNA polymerase cleaves the 5′ end of host pre-mRNAs and uses the capped RNA fragments as primers for viral mRNA synthesis. We performed deep sequencing of the 5′ ends of viral mRNAs from all genome segments transcribed in both human (A549) and mouse (M-1) cells infected with th...

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Detalhes bibliográficos
Main Authors: Sikora, Dorota, Rocheleau, Lynda, Brown, Earl G., Pelchat, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143772/
https://ncbi.nlm.nih.gov/pubmed/25154590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep06181
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