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Detecting longitudinal effects of haplotypes and smoking on hypertension using B-splines and Bayesian LASSO

The behavior of a gene can be dynamic; thus, if longitudinal data are available, it is important that we study the dynamic effects of genes on a trait over time. The effect of a haplotype can be expressed by time-varying coefficients. In this paper, we use the natural cubic B-spline to express these...

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Hlavní autoři: Xia, Shuang, Lin, Shili
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143712/
https://ncbi.nlm.nih.gov/pubmed/25519413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-8-S1-S85
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