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Identifying cryptic population structure in multigenerational pedigrees in a Mexican American sample

Cryptic population structure can increase both type I and type II errors. This is particularly problematic in case-control association studies of unrelated individuals. Some researchers believe that these problems are obviated in families. We argue here that this may not be the case, especially if f...

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Detalhes bibliográficos
Main Authors: Culverhouse, Robert C, Hinrichs, Anthony L, Suarez, Brian K
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143674/
https://ncbi.nlm.nih.gov/pubmed/25519323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-8-S1-S4
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