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Effects of initial boost with TGF-beta 1 and grade of intervertebral disc degeneration on 3D culture of human annulus fibrosus cells

BACKGROUND: Three-dimensional (3D) culture in porous biomaterials as well as stimulation with growth factors are known to be supportive for intervertebral disc cell differentiation and tissue formation. Unless sophisticated releasing systems are used, however, effective concentrations of growth fact...

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Detalhes bibliográficos
Main Authors: Hegewald, Aldemar Andres, Cluzel, Jessie, Krüger, Jan Philipp, Endres, Michaela, Kaps, Christian, Thomé, Claudius
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143571/
https://ncbi.nlm.nih.gov/pubmed/25116605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13018-014-0073-8
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