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Epigenome-wide association study reveals longitudinally stable DNA methylation differences in CD4+ T cells from children with IgE-mediated food allergy

Food allergy is mediated by a combination of genetic and environmental risk factors, potentially mediated by epigenetic mechanisms. CD4+ T-cells are key drivers of the allergic response, and may therefore harbor epigenetic variation in association with the disease phenotype. Here we retrospectively...

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Detalhes bibliográficos
Main Authors: Martino, David, Joo, Jihoon E, Sexton-Oates, Alexandra, Dang, Thanh, Allen, Katrina, Saffery, Richard, Prescott, Susan
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143415/
https://ncbi.nlm.nih.gov/pubmed/24762976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.28945
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