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Longitudinal epigenetic drift in mice perinatally exposed to lead

An understanding of the natural change in DNA methylation over time, defined as “epigenetic drift,” will inform the study of environmental effects on the epigenome. This study investigates epigenetic drift in isogenic mice exposed perinatally to lead (Pb) acetate at four concentrations, 0 ppm (contr...

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Bibliographic Details
Main Authors: Faulk, Christopher, Liu, Kevin, Barks, Amanda, Goodrich, Jaclyn M, Dolinoy, Dana C
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143408/
https://ncbi.nlm.nih.gov/pubmed/24786859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.29024
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