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Integrin β1 regulates leiomyoma cytoskeletal integrity and growth

Uterine leiomyomas are characterized by an excessive extracellular matrix, increased mechanical stress, and increased active RhoA. Previously, we observed that mechanical signaling was attenuated in leiomyoma, but the mechanisms responsible remain unclear. Integrins, especially integrin β1, are tran...

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Библиографические подробности
Главные авторы: Malik, Minnie, Segars, James, Catherino, William H.
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143333/
https://ncbi.nlm.nih.gov/pubmed/23023061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2012.09.005
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