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Evaluation of a (64)Cu-Labeled Cystine-Knot Peptide Based on Agouti-Related Protein for PET of Tumors Expressing α(v)β(3) Integrin

Recently, a truncated form of the agouti-related protein (AgRP), a 4-kDa cystine-knot peptide of human origin, was used as a scaffold to engineer mutants that bound to α(v)β(3) integrin with high affinity and specificity. In this study, we evaluated the potential of engineered integrin-binding AgRP...

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Detalhes bibliográficos
Main Authors: Jiang, Lei, Kimura, Richard H., Miao, Zheng, Silverman, Adam P., Ren, Gang, Liu, Hongguang, Li, Peiyong, Gambhir, Sanjiv Sam, Cochran, Jennifer R., Cheng, Zhen
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143171/
https://ncbi.nlm.nih.gov/pubmed/20124048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.109.069831
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