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Convergent synthetic methodology for the construction of self-adjuvanting lipopeptide vaccines using a novel carbohydrate scaffold

A novel convergent synthetic strategy for the construction of multicomponent self-adjuvanting lipopeptide vaccines was developed. A tetraalkyne-functionalized glucose derivative and lipidated Fmoc-lysine were prepared by novel efficient and convenient syntheses. The carbohydrate building block was c...

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Détails bibliographiques
Auteurs principaux: Fagan, Vincent, Toth, Istvan, Simerska, Pavla
Format: Artigo
Langue:Inglês
Publié: Beilstein-Institut 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143089/
https://ncbi.nlm.nih.gov/pubmed/25161732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.10.181
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