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Convergent synthetic methodology for the construction of self-adjuvanting lipopeptide vaccines using a novel carbohydrate scaffold

A novel convergent synthetic strategy for the construction of multicomponent self-adjuvanting lipopeptide vaccines was developed. A tetraalkyne-functionalized glucose derivative and lipidated Fmoc-lysine were prepared by novel efficient and convenient syntheses. The carbohydrate building block was c...

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Detaylı Bibliyografya
Asıl Yazarlar: Fagan, Vincent, Toth, Istvan, Simerska, Pavla
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Beilstein-Institut 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143089/
https://ncbi.nlm.nih.gov/pubmed/25161732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.10.181
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