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Multivalent scaffolds induce galectin-3 aggregation into nanoparticles

Galectin-3 meditates cell surface glycoprotein clustering, cross linking, and lattice formation. In cancer biology, galectin-3 has been reported to play a role in aggregation processes that lead to tumor embolization and survival. Here, we show that lactose-functionalized dendrimers interact with ga...

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Bibliografski detalji
Glavni autori: Goodman, Candace K, Wolfenden, Mark L, Nangia-Makker, Pratima, Michel, Anna K, Raz, Avraham, Cloninger, Mary J
Format: Artigo
Jezik:Inglês
Izdano: Beilstein-Institut 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4142985/
https://ncbi.nlm.nih.gov/pubmed/25161713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.10.162
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