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Clicked and long spaced galactosyl- and lactosylcalix[4]arenes: new multivalent galectin-3 ligands

Four novel calix[4]arene-based glycoclusters were synthesized by conjugating the saccharide units to the macrocyclic scaffold using the CuAAC reaction and using long and hydrophilic ethylene glycol spacers. Initially, two galactosylcalix[4]arenes were prepared starting from saccharide units and cali...

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Bibliographische Detailangaben
Hauptverfasser: Bernardi, Silvia, Fezzardi, Paola, Rispoli, Gabriele, Sestito, Stefania E, Peri, Francesco, Sansone, Francesco, Casnati, Alessandro
Format: Artigo
Sprache:Inglês
Veröffentlicht: Beilstein-Institut 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4142870/
https://ncbi.nlm.nih.gov/pubmed/25161726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.10.175
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