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C–H-Functionalization logic guides the synthesis of a carbacyclopamine analog
The chemical synthesis of carbacyclopamine analog 2, a cyclopamine analog with an all-carbon E-ring, is reported. The use of C–H-functionalization logic and further metal-catalyzed transformations allows for a concise entry to this new class of acid-stable cyclopamine analogs.
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Beilstein-Institut
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4142839/ https://ncbi.nlm.nih.gov/pubmed/25161712 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.10.161 |
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