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Stem cells, the molecular circuitry of pluripotency and nuclear reprogramming

Reprogramming of somatic cells to a pluripotent embryonic stem cell-like state has been achieved by nuclear transplantation of a somatic nucleus into an enucleated egg and most recently by introducing defined transcription factors into somatic cells. Nuclear reprogramming is of great medical interes...

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Autors principals: Jaenisch, Rudolf, Young, Richard
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4142810/
https://ncbi.nlm.nih.gov/pubmed/18295576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.01.015
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