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L-Type Ca(2+) Channel Responses to Bay K 8644 in Stem Cell-Derived Cardiomyocytes Are Unusually Dependent on Holding Potential and Charge Carrier

Human stem cell-derived cardiomyocytes provide a cellular model for the study of electrophysiology in the human heart and are finding a niche in the field of safety pharmacology for predicting proarrhythmia. The cardiac L-type Ca(2+) channel is an important target for some of these safety studies. H...

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Detalhes bibliográficos
Main Authors: Ji, Junzhi, Kang, Jiesheng, Rampe, David
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4142808/
https://ncbi.nlm.nih.gov/pubmed/25147907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/adt.2014.596
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