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Comet assay to measure DNA repair: approach and applications
Cellular repair enzymes remove virtually all DNA damage before it is fixed; repair therefore plays a crucial role in preventing cancer. Repair studied at the level of transcription correlates poorly with enzyme activity, and so assays of phenotype are needed. In a biochemical approach, substrate nuc...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4142706/ https://ncbi.nlm.nih.gov/pubmed/25202323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2014.00288 |
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