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An aspartyl cathepsin, CTH3, is essential for proprotein processing during secretory granule maturation in Tetrahymena thermophila

In Tetrahymena thermophila, peptides secreted via dense-core granules, called mucocysts, are generated by proprotein processing. We used expression profiling to identify candidate processing enzymes, which localized as cyan fluorescent protein fusions to mucocysts. Of note, the aspartyl cathepsin Ct...

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Detalles Bibliográficos
Main Authors: Kumar, Santosh, Briguglio, Joseph S., Turkewitz, Aaron P.
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Cell Biology 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4142616/
https://ncbi.nlm.nih.gov/pubmed/24943840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-03-0833
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