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An aspartyl cathepsin, CTH3, is essential for proprotein processing during secretory granule maturation in Tetrahymena thermophila

In Tetrahymena thermophila, peptides secreted via dense-core granules, called mucocysts, are generated by proprotein processing. We used expression profiling to identify candidate processing enzymes, which localized as cyan fluorescent protein fusions to mucocysts. Of note, the aspartyl cathepsin Ct...

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Detalhes bibliográficos
Main Authors: Kumar, Santosh, Briguglio, Joseph S., Turkewitz, Aaron P.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4142616/
https://ncbi.nlm.nih.gov/pubmed/24943840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-03-0833
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