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Effects of high glucose on integrin activity and fibronectin matrix assembly by mesangial cells
The filtration unit of the kidney is the glomerulus, a capillary network supported by mesangial cells and extracellular matrix (ECM). Glomerular function is compromised in diabetic nephropathy (DN) by uncontrolled buildup of ECM, especially type IV collagen, which progressively occludes the capillar...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The American Society for Cell Biology
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4142608/ https://ncbi.nlm.nih.gov/pubmed/24943838 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-03-0800 |
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