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Combinatorial Enzymatic Synthesis of Heparan Sulfate
Escherichia coli K5 heparosan was enzymatically modified by Chen and colleagues [10] to construct a library of heparan sulfate polysaccharides for evaluation, leading to the discovery that a 2-O-sulfo-iduronic acid residue is not essential for antithrombin-mediated anticoagulant activity in larger o...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4142598/ https://ncbi.nlm.nih.gov/pubmed/17884627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2007.09.002 |
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