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Conservation of the DENV-2 type-specific and DEN complex-reactive antigenic sites among DENV-2 genotypes

The envelope (E) protein is composed of three domains (ED1, ED2 and ED3) with ED3 targeted by the most potent neutralizing antibodies. DENV-2 strains can be divided into six genotypes. Comparison of ED3 of representative strains of the six genotypes revealed that there are nine variable residues tha...

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Detalhes bibliográficos
Main Authors: Pitcher, Trevor J., Gromowski, Gregory D., Beasley, David W.C., Barrett, Alan D.T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4142575/
https://ncbi.nlm.nih.gov/pubmed/22153298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2011.10.020
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