Diet-induced obesity promotes myelopoiesis in hematopoietic stem cells

Obesity is associated with an activated macrophage phenotype in multiple tissues that contributes to tissue inflammation and metabolic disease. To evaluate the mechanisms by which obesity potentiates myeloid activation, we evaluated the hypothesis that obesity activates myeloid cell production from...

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Autori principali: Singer, Kanakadurga, DelProposto, Jennifer, Lee Morris, David, Zamarron, Brian, Mergian, Taleen, Maley, Nidhi, Cho, Kae Won, Geletka, Lynn, Subbaiah, Perla, Muir, Lindsey, Martinez-Santibanez, Gabriel, Nien-Kai Lumeng, Carey
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2014
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4142398/
https://ncbi.nlm.nih.gov/pubmed/25161889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2014.06.005
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