Novel and optimized strategies for inducing fibrosis in vivo: focus on Duchenne Muscular Dystrophy

BACKGROUND: Fibrosis, an excessive collagen accumulation, results in scar formation, impairing function of vital organs and tissues. Fibrosis is a hallmark of muscular dystrophies, including the lethal Duchenne muscular dystrophy (DMD), which remains incurable. Substitution of muscle by fibrotic tis...

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Main Authors: Pessina, Patrizia, Cabrera, Daniel, Morales, María Gabriela, Riquelme, Cecilia A, Gutiérrez, Jaime, Serrano, Antonio L, Brandan, Enrique, Muñoz-Cánoves, Pura
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Methodology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4142391/
https://ncbi.nlm.nih.gov/pubmed/25157321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2044-5040-4-7
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