Bcl-2 Family Proteins Are Involved in the Signal Crosstalk between Endoplasmic Reticulum Stress and Mitochondrial Dysfunction in Tumor Chemotherapy Resistance

Tumor cells overexpress antiapoptotic proteins of the Bcl-2 (B-cell leukemia/lymphoma-2) family, which can lead to both escape from cell death and resistance to chemotherapeutic drugs. Recent studies suggest that the endoplasmic reticulum (ER) can produce proapoptotic signals, amplifying the apoptot...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Su, Jing, Zhou, Lei, Xia, Mei-hui, Xu, Ye, Xiang, Xi-yan, Sun, Lian-kun
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Hindawi Publishing Corporation 2014
Θέματα:
Review Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4142381/
https://ncbi.nlm.nih.gov/pubmed/25177684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/234370
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