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Synthesis and evaluation of a pyrazinoic acid prodrug in Mycobacterium tuberculosis

Tuberculosis (TB) is a disease caused mainly by infection of Mycobacterium tuberculosis affecting more than ten million people around the world. Despite TB can be treated, the rise of MDR-TB and XDR-TB cases put the disease in a worrying status. As pyrazinamide-resistant strains exhibit low or none...

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Detalhes bibliográficos
Main Authors: Fernandes, João Paulo-dos Santos, Pavan, Fernando Rogerio, Leite, Clarice Queico Fujimura, Felli, Veni Maria Andres
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4142361/
https://ncbi.nlm.nih.gov/pubmed/25161383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsps.2013.12.005
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