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Gene Behavior Interaction of Depressive Symptoms and the Apolipoprotein E ε4 Allele on Cognitive Decline

OBJECTIVE: Depressive symptoms and the APOE ε4 allele are independent risk factors for cognitive decline. However, it is not clear whether the presence of both depressive symptoms and the APOE ε4 allele increases cognitive decline. METHODS: A prospective study of a population-based sample of 4,150 (...

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Détails bibliographiques
Auteurs principaux: Rajan, Kumar B., Wilson, Robert S., Skarupski, Kimberly A., de Leon, Carlos Mendes, Evans, Denis A.
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4142223/
https://ncbi.nlm.nih.gov/pubmed/24434953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PSY.0000000000000029
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