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Gene Behavior Interaction of Depressive Symptoms and the Apolipoprotein E ε4 Allele on Cognitive Decline

OBJECTIVE: Depressive symptoms and the APOE ε4 allele are independent risk factors for cognitive decline. However, it is not clear whether the presence of both depressive symptoms and the APOE ε4 allele increases cognitive decline. METHODS: A prospective study of a population-based sample of 4,150 (...

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Autors principals: Rajan, Kumar B., Wilson, Robert S., Skarupski, Kimberly A., de Leon, Carlos Mendes, Evans, Denis A.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4142223/
https://ncbi.nlm.nih.gov/pubmed/24434953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PSY.0000000000000029
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