ZMYND11 links histone H3.3 K36 trimethylation to transcription elongation and tumor suppression

Recognition of modified histones by “reader” proteins plays a critical role in the regulation of chromatin(1). H3K36 trimethylation (H3K36me3) is deposited onto the nucleosomes in the transcribed regions following RNA polymerase II (Pol II) elongation. In yeast, this mark in turn recruits epigenetic...

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Hauptverfasser: Wen, Hong, Li, Yuanyuan, Xi, Yuanxin, Jiang, Shiming, Stratton, Sabrina, Peng, Danni, Tanaka, Kaori, Ren, Yongfeng, Xia, Zheng, Wu, Jun, Li, Bing, Barton, Michelle C., Li, Wei, Li, Haitao, Shi, Xiaobing
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4142212/
https://ncbi.nlm.nih.gov/pubmed/24590075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13045
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