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Interleukin-6 and C-reactive protein as predictors of cognitive decline in late midlife

OBJECTIVE: Peripheral inflammatory markers are elevated in patients with dementia. In order to assess their etiologic role, we examined whether interleukin-6 (IL-6) and C-reactive protein (CRP) measured in midlife predict concurrently assessed cognition and subsequent cognitive decline. METHODS: Mea...

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Main Authors: Singh-Manoux, Archana, Dugravot, Aline, Brunner, Eric, Kumari, Meena, Shipley, Martin, Elbaz, Alexis, Kivimaki, Mika
Format: Artigo
Jezik:Inglês
Izdano: Lippincott Williams & Wilkins 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4141998/
https://ncbi.nlm.nih.gov/pubmed/24991031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000000665
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