Optogenetic Recruitment of Dorsal Raphe Serotonergic Neurons Acutely Decreases Mechanosensory Responsivity in Behaving Mice

The inhibition of sensory responsivity is considered a core serotonin function, yet this hypothesis lacks direct support due to methodological obstacles. We adapted an optogenetic approach to induce acute, robust and specific firing of dorsal raphe serotonergic neurons. In vitro, the responsiveness...

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Main Authors: Dugué, Guillaume P., Lörincz, Magor L., Lottem, Eran, Audero, Enrica, Matias, Sara, Correia, Patricia A., Léna, Clément, Mainen, Zachary F.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4141837/
https://ncbi.nlm.nih.gov/pubmed/25148042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0105941
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