Optogenetic Recruitment of Dorsal Raphe Serotonergic Neurons Acutely Decreases Mechanosensory Responsivity in Behaving Mice

The inhibition of sensory responsivity is considered a core serotonin function, yet this hypothesis lacks direct support due to methodological obstacles. We adapted an optogenetic approach to induce acute, robust and specific firing of dorsal raphe serotonergic neurons. In vitro, the responsiveness...

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Bibliografiska uppgifter
Huvudupphovsmän: Dugué, Guillaume P., Lörincz, Magor L., Lottem, Eran, Audero, Enrica, Matias, Sara, Correia, Patricia A., Léna, Clément, Mainen, Zachary F.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2014
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4141837/
https://ncbi.nlm.nih.gov/pubmed/25148042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0105941
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