Evaluation of Naturally Acquired IgG Antibodies to a Chimeric and Non-Chimeric Recombinant Species of Plasmodium vivax Reticulocyte Binding Protein-1: Lack of Association with HLA-DRB1*/DQB1* in Malaria Exposed Individuals from the Brazilian Amazon

The development of modular constructs that include antigenic regions targeted by protective immune responses is an attractive approach for subunit vaccine development. However, a main concern of using these vaccine platforms is how to preserve the antigenic identity of conformational B cell epitopes...

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Main Authors: Ferreira, Amanda Ribeiro, Singh, Balwan, Cabrera-Mora, Monica, Magri De Souza, Alana Cristina, Queiroz Marques, Maria Teresa, Porto, Luis Cristovão Sobrino, Santos, Fatima, Banic, Dalma Maria, Calvo-Calle, J. Mauricio, Oliveira-Ferreira, Joseli, Moreno, Alberto, Da Costa Lima-Junior, Josué
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4141821/
https://ncbi.nlm.nih.gov/pubmed/25148251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0105828
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