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Inhibition of c-Abl Kinase Activity Renders Cancer Cells Highly Sensitive to Mitoxantrone
Although c-Abl has increasingly emerged as a key player in the DNA damage response, its role in this context is far from clear. We studied the effect of inhibition of c-Abl kinase activity by imatinib with chemotherapy drugs and found a striking difference in cell survival after combined mitoxantron...
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Hlavní autoři: | , , , , , , , , |
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Médium: | Artigo |
Jazyk: | Inglês |
Vydáno: |
Public Library of Science
2014
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Témata: | |
On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4141754/ https://ncbi.nlm.nih.gov/pubmed/25148385 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0105526 |
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