Multiple system atrophy as emerging template for accelerated drug discovery in α-synucleinopathies

There is evidence that the α-synucleinopathies Parkinson's disease (PD) and the Parkinson variant of multiple system atrophy (MSA-P) overlap at multiple levels. Both disorders are characterized by deposition of abnormally phosphorylated fibrillar α-synuclein within the central nervous system su...

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Autori principali: Krismer, Florian, Jellinger, Kurt A., Scholz, Sonja W., Seppi, Klaus, Stefanova, Nadia, Antonini, Angelo, Poewe, Werner, Wenning, Gregor K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier Science 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4141743/
https://ncbi.nlm.nih.gov/pubmed/24894118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.parkreldis.2014.05.005
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