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Simultaneous and independent tuning of RhoA and Rac1 activity with orthogonally inducible promoters
The GTPases RhoA and Rac1 are key regulators of cell spreading, adhesion, and migration, and they exert distinct effects on the actin cytoskeleton. While RhoA classically stimulates stress fiber assembly and contraction, Rac1 promotes branched actin polymerization and membrane protrusion. These comp...
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| Huvudupphovsmän: | , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2014
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4141552/ https://ncbi.nlm.nih.gov/pubmed/25044255 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4ib00099d |
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