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Systemic Lipopolysaccharide Induces Cochlear Inflammation and Exacerbates the Synergistic Ototoxicity of Kanamycin and Furosemide

Aminoglycoside antibiotics are highly effective agents against gram-negative bacterial infections, but they cause adverse effects on hearing and balance dysfunction as a result of toxicity to hair cells of the cochlea and vestibular organs. While ototoxicity has been comprehensively studied, the con...

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Sonraí Bibleagrafaíochta
Main Authors: Hirose, Keiko, Li, Song-Zhe, Ohlemiller, Kevin K., Ransohoff, Richard M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Springer US 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4141430/
https://ncbi.nlm.nih.gov/pubmed/24845404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10162-014-0458-8
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