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The link between the GBA gene and parkinsonism

Mutations in the glucocerebrosidase (GBA) gene, which encodes the lysosomal enzyme that is deficient in Gaucher's disease, are important and common risk factors for Parkinson’s disease and related disorders. This association was first recognised in the clinic, where parkinsonism was noted, albe...

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Detalhes bibliográficos
Main Authors: Sidransky, Ellen, Lopez, Grisel
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4141416/
https://ncbi.nlm.nih.gov/pubmed/23079555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1474-4422(12)70190-4
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