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Ornithine cyclodeaminase/μ-crystallin homolog from the hyperthermophilic archaeon Thermococcus litoralis functions as a novel Δ(1)-pyrroline-2-carboxylate reductase involved in putative trans-3-hydroxy-l-proline metabolism

l-Ornithine cyclodeaminase (OCD) is involved in l-proline biosynthesis and catalyzes the unique deaminating cyclization of l-ornithine to l-proline via a Δ(1)-pyrroline-2-carboxyrate (Pyr2C) intermediate. Although this pathway functions in only a few bacteria, many archaea possess OCD-like genes (pr...

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Detalhes bibliográficos
Main Authors: Watanabe, Seiya, Tozawa, Yuzuru, Watanabe, Yasuo
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4141209/
https://ncbi.nlm.nih.gov/pubmed/25161870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fob.2014.07.005
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