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Genetic and laboratory diagnostic approach in Niemann Pick disease type C

Niemann Pick disease type C (NP-C) is a rare autosomal recessive disorder that results from mutations in either the NPC1 or the NPC2 gene. The estimated incidence of NP-C is 1 in 120,000 live births, although the frequency of cases is higher in some isolated populations. More than 350 different NPC1...

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Autors principals: McKay Bounford, K., Gissen, P.
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4141153/
https://ncbi.nlm.nih.gov/pubmed/25145893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00415-014-7386-8
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