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More ethical and more efficient clinical research: multiplex trial design

BACKGROUND: Today’s clinical research faces challenges such as a lack of clinical equipoise between treatment arms, reluctance in randomizing for multiple treatments simultaneously, inability to address interactions and increasingly restricted resources. Furthermore, many trials are biased by extens...

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Autors principals: Keus, Frederik, van der Horst, Iwan CC, Nijsten, Maarten W
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4141104/
https://ncbi.nlm.nih.gov/pubmed/25125365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-7-530
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