Binding of Streptococcus pneumoniae Endopeptidase O (PepO) to Complement Component C1q Modulates the Complement Attack and Promotes Host Cell Adherence

The Gram-positive species Streptococcus pneumoniae is a human pathogen causing severe local and life-threatening invasive diseases associated with high mortality rates and death. We demonstrated recently that pneumococcal endopeptidase O (PepO) is a ubiquitously expressed, multifunctional plasminoge...

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Détails bibliographiques
Auteurs principaux: Agarwal, Vaibhav, Sroka, Magdalena, Fulde, Marcus, Bergmann, Simone, Riesbeck, Kristian, Blom, Anna M.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2014
Sujets:
Immunology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140937/
https://ncbi.nlm.nih.gov/pubmed/24739385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.530212
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