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Functional Rescue of Kallmann Syndrome-associated Prokineticin Receptor 2 (PKR2) Mutants Deficient in Trafficking

Mutations in the G protein-coupled prokineticin receptor 2 (PKR2) are known to cause Kallmann syndrome and idiopathic hypogonadotropic hypogonadism manifesting with delayed puberty and infertility. Some of the mutant receptors are not routed to the cell surface; instead, they are trapped in the cell...

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Detalhes bibliográficos
Main Authors: Chen, Dan-Na, Ma, Yan-Tao, Liu, Huadie, Zhou, Qun-Yong, Li, Jia-Da
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140907/
https://ncbi.nlm.nih.gov/pubmed/24753254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.556381
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