Reciprocal Changes in Phosphorylation and Methylation of Mammalian Brain Sodium Channels in Response to Seizures

Voltage-gated sodium (Nav) channels initiate action potentials in brain neurons and are primary therapeutic targets for anti-epileptic drugs controlling neuronal hyperexcitability in epilepsy. The molecular mechanisms underlying abnormal Nav channel expression, localization, and function during deve...

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Bibliografski detalji
Glavni autori: Baek, Je-Hyun, Rubinstein, Moran, Scheuer, Todd, Trimmer, James S.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2014
Teme:
Neurobiology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140893/
https://ncbi.nlm.nih.gov/pubmed/24737319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.562785
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