Diffusion Tensor and Volumetric Magnetic Resonance Measures as Biomarkers of Brain Damage in a Small Animal Model of HIV

BACKGROUND: There are currently no widely accepted neuro-HIV small animal models. We wanted to validate the HIV-1 Transgenic rat (Tg) as an appropriate neuro-HIV model and then establish in vivo imaging biomarkers of neuropathology, within this model, using MR structural and diffusion tensor imaging...

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Autors principals: Lentz, Margaret R., Peterson, Kristin L., Ibrahim, Wael G., Lee, Dianne E., Sarlls, Joelle, Lizak, Martin J., Maric, Dragan, Reid, William C., Hammoud, Dima A.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140825/
https://ncbi.nlm.nih.gov/pubmed/25144656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0105752
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