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Covalent Defects Restrict Supramolecular Self-Assembly of Homopolypeptides: Case Study of β(2)-Fibrils of Poly-L-Glutamic Acid

Poly-L-glutamic acid (PLGA) often serves as a model in studies on amyloid fibrils and conformational transitions in proteins, and as a precursor for synthetic biomaterials. Aggregation of PLGA chains and formation of amyloid-like fibrils was shown to continue on higher levels of superstructural self...

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Detalhes bibliográficos
Main Authors: Fulara, Aleksandra, Hernik, Agnieszka, Nieznańska, Hanna, Dzwolak, Wojciech
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140804/
https://ncbi.nlm.nih.gov/pubmed/25144464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0105660
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