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Upregulation of Intermediate-Conductance Ca(2+)-Activated K(+) Channels (KCNN4) in Porcine Coronary Smooth Muscle Requires NADPH Oxidase 5 (NOX5)

AIMS: NADPH oxidase (NOX) is the primary source of reactive oxygen species (ROS) in vascular smooth muscle cells (SMC) and is proposed to play a key role in redox signaling involved in the pathogenesis of cardiovascular disease. Growth factors and cytokines stimulate coronary SMC (CSMC) phenotypic m...

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Autors principals: Gole, Hope K. A., Tharp, Darla L., Bowles, Douglas K.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140784/
https://ncbi.nlm.nih.gov/pubmed/25144362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0105337
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